The following Mega Millions and Powerball jackpots produced the Best ten most significant lottery jackpots in U.S. history, as of Jan. 21, 2023. The Powerball drawing on March 30, 2005, created 110 second-prize winners. The total payout to these winners was $19.4 million, with 89 winners getting $100,000 each and every, when the other 21 winners r